I’ve had some tendonitis in my elbows predating the SD. Using it can trigger the elbow pain. It depends a lot on my posture and the game controls (back buttons are especially bad). I ended up buying some grips on etc to keep my fingers from clenching so hard.

I use it in desktop mode periodically. If it’s already docked and I need a browser that isn’t on my phone, I’ll use it rather than swap over to my work laptop. I’ve been on linux for decades, so it’s pretty comfy for me,