Project Hail Mass Effect. Very spacy, lots of aliens.

Odyssey x Shattered Pixel Dungeon

Lowkey, that would actually be a sick game, Greek flavored pixel dungeon.

Obsession and Balders Gate 3

I guess some more curses and demonic like storylines lol

Dark Souls III x Stargate

Watchmen x Splatoon is a very uhh interesting combination

Grim Dawn x The Odyssey. Honestly aside from the addition of guns in ancient Greece times and the Gods is basically magic usage, it would probably not be too odd. I’d play it

Minecraft with Leslie nielsen would be rather funny. Just an idea ripe for comedy I would think

A Dune mod for Minecraft would actually be kinda sick. Riding a giant sand worm thru a desert? Yes please.

Jackie Chan and Owen Wilson stranded on a remote island after their plane crashes, they must climb above the rising fog to signal to rescuers. Many hijinks, maybe some kung fu against skeletons, Owen saying “wow” while tripping on shrooms, fun for the whole PG13 family.

The Man From Nowhere + Slime Rancher…so seedy underworld trafficking anthropomorphic slimes?

Rouge Trader von Volancius returning back in time over and over again to the same dining hall to pick a team that can stop a sentient AI from emerging and enslaving Humankind Empire in virtual reality.

Actually, this looks like a valid Warhammer 40k plot.

Movie: Lady Macbeth
Game: Vampire survivors

In this crossover you will play as Katherine Lester, who is pestered by an unending army of in-laws. She defends herself with poisonous mushrooms, a fireplace poke, a shotgun to shoot the horses and a pillow to smother the children with. Health can be regenerated by hopping in bed with workman Sebastian, but he’s not easy to find.

Obsession and Factorio.

“I wish that Rat loved me more than any game in the world.” And it has no effect because I’d already give up my life or kill for this game.

Hook and Vintage Story. I think I just killed the Lost Boys with Eldridge Horrors beyond comprehension, accidentally.

Spider-Man Brand New Day and Batman: Arkham City

Pretty much a crossover comic event.