New diet villain just dropped. Believe or disbelieve this specific one, "fat" or even "polyunsaturated fat" increasingly looks like a failure as a natural category. Only finer-grained concepts like "linoleic acid" are useful for carving reality at the joints.
Some meta-analyses do kinda have the vibe of collateralized debt obligations and credit default swaps, combining weak studies and claiming a strong result. (Case in point: some of the bogus studies of ivermectin etc for covid). Not all of them, but if you’re not working in a field (and good at evaluating methods etc) you probably should wait for someone in the field to evaluate meta-analyses in the field.
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Some meta-analyses do kinda have the vibe of collateralized debt obligations and credit default swaps, combining weak studies and claiming a strong result. (Case in point: some of the bogus studies of ivermectin etc for covid). Not all of them, but if you’re not working in a field (and good at evaluating methods etc) you probably should wait for someone in the field to evaluate meta-analyses in the field.