I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
I feel bad for Meša Selimović, a Yugoslav writer. Poor dude joined communist resistance forces with his brothers during WWII, only for one of his brothers to later be falsely accused as a thief and killed without a trial by the very same communist government they fought and bled for